STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0661Predicted coding region TP0661; Hypothetical protein; identified by Glimmer; putative. (170 aa)    
Predicted Functional Partners:
flgK
Flagellar hook-associated protein 1 (flgK); Similar to SP:P70859 PID:1518046 GB:AE000783 percent identity: 39.78; identified by sequence similarity; putative.
   
   0.767
flgL
Flagellar hook-associated protein 3 (flgL); Similar to GP:1518047 percent identity: 29.50; identified by sequence similarity; putative.
       0.578
flaA3
Flagellar filament outer layer protein (flaA-2); Similar to GP:2108245 percent identity: 97.83; identified by sequence similarity; putative.
   
   0.567
csrA
Carbon storage regulator (csrA); A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
       0.554
fliW
Transmembrane protein, putative; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. Belongs to the FliW family.
       0.554
fba
Fructose-bisphosphate aldolase (cbbA); Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
       0.501
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.