STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0706Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 36.30; identified by sequence similarity; putative. (308 aa)    
Predicted Functional Partners:
mrcA
Penicillin-binding protein (pbp-2); Similar to GB:AE000783 percent identity: 40.76; identified by sequence similarity; putative.
 
   
 0.733
TP_0806
femA protein, putative; Similar to GB:AE000783 percent identity: 32.57; identified by sequence similarity; putative.
      
 0.676
TP_0707
Predicted coding region TP0707; Hypothetical protein; identified by Glimmer; putative.
       0.592
TP_0711
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.11; identified by sequence similarity; putative.
    
  0.554
TP_0623
Membrane-bound lytic murein transglycosylase D (dniR); Similar to SP:P23931 GB:X60739 PID:1208972 PID:581068 GB:U00096 percent identity: 32.28; identified by sequence similarity; putative.
  
 
 0.475
tpn50
Outer membrane protein (tpn50); Could function as a porin; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
  
  0.456
fliM
Flagellar motor switch protein (fliM); FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
    
   0.449
TP_0444
Conserved hypothetical protein; Similar to PID:887815 GB:U00096 PID:1789228 percent identity: 30.14; identified by sequence similarity; putative.
  
   
 0.446
TP_0702
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.72; identified by sequence similarity; putative.
 
    
0.437
TP_0708
Predicted coding region TP0708; Hypothetical protein; identified by Glimmer; putative.
       0.436
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.