STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0711Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.11; identified by sequence similarity; putative. (190 aa)    
Predicted Functional Partners:
flhF
Flagellar-associated GTP-binding protein (flhF); Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum (By similarity); Belongs to the GTP-binding SRP family.
   
   0.843
TP_0710
Conserved hypothetical protein; Similar to PID:1165252 GB:AE000783 percent identity: 32.48; identified by sequence similarity; putative.
     
 0.818
ftsK
Cell division protein, putative; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family.
    
 
 0.788
TP_0486
Antigen, p83/100; Similar to PID:928980 PID:928982 PID:928985 PID:1272517 GB:AE000783 percent identity: 26.14; identified by sequence similarity; putative.
    
 0.778
TP_0709
RNA polymerase sigma-28 factor; Similar to GB:J03169 SP:P17211 PID:153486 PID:153487 percent identity: 47.79; identified by sequence similarity; putative; Belongs to the sigma-70 factor family.
       0.772
flaB3
Flagellar filament 31 kDa core protein (flaB3); Component of the core of the flagella.
    
   0.761
TP_0434
Predicted coding region TP0434; Hypothetical protein; identified by Glimmer; putative.
  
  0.704
rpoE
RNA polymerase sigma-24 factor (rpoE); Similar to PID:699142 percent identity: 27.89; identified by sequence similarity; putative.
    
 0.664
fklB
Peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB); Similar to GB:U14003 SP:P39311 PID:537048 GB:U00096 PID:1790652 percent identity: 43.46; identified by sequence similarity; putative.
    
  0.613
smc
Chromosome segregation protein, putative; Required for chromosome condensation and partitioning. Belongs to the SMC family.
   
 
 0.574
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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