STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliOHypothetical protein; Similar to PID:1216382 PID:973196 percent identity: 100.00; identified by sequence similarity; putative. (262 aa)    
Predicted Functional Partners:
fliY
Flagellar motor switch protein (fliY); FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
  
 0.998
fliQ
Flagellar biosynthetic protein (fliQ); Role in flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family.
  
  
 0.997
fliP
Flagellar biosynthetic protein (fliP); Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
  
  
 0.997
flhA
Flagellar biosynthesis protein (flhA); Involved in the export of flagellum proteins; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
  
  
 0.996
fliR
Flagellar biosynthetic protein (fliR); Role in flagellar biosynthesis; Belongs to the FliR/MopE/SpaR family.
  
  
 0.996
flhB
Flagellar biosynthetic protein (flhB); Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity); Belongs to the type III secretion exporter family.
  
  
 0.995
fliM
Flagellar motor switch protein (fliM); FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
  
 
 0.992
fliL
Flagellar protein (fliL); Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
 
 0.984
fliF
Flagellar basal-body M ring protein (fliF); The M ring may be actively involved in energy transduction.
 
  
 0.982
fliH
Flagellar assembly protein (fliH); Needed for flagellar regrowth and assembly; Belongs to the FliH family.
 
  
 0.980
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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