STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgsA2Conserved hypothetical protein; Similar to PID:2088865 percent identity: 28.12; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (365 aa)    
Predicted Functional Partners:
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (pgsA); This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.941
cdsA
Phosphatidate cytidylyltransferase (cdsA); Similar to GB:AE000783 percent identity: 32.47; identified by sequence similarity; putative.
    
 0.886
TP_0334
Conserved hypothetical protein; Similar to GP:1842438 percent identity: 31.48; identified by sequence similarity; putative.
  
    0.828
TP_0731
Conserved hypothetical protein; Similar to PID:1652491 percent identity: 36.19; identified by sequence similarity; putative; Belongs to the Nudix hydrolase family.
  
    0.740
glpQ
Glycerophosphoryldiester phosphodiesterase (glpQ); Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols.
   
 0.721
folD
Methylenetetrahydrofolate dehydrogenase (folD); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
  
 0.718
TP_0304
Predicted coding region TP0304; Hypothetical protein; identified by Glimmer; putative.
 
     0.696
TP_0551
Phosphatase; Similar to GB:L25421 PID:409159 percent identity: 32.50; identified by sequence similarity; putative.
 
 
 0.674
TP_0622
Predicted coding region TP0622; Hypothetical protein; identified by Glimmer; putative.
  
     0.643
TP_0671
Sn-1,2-diacylglycerol cholinephosphotransferase, putative; Similar to SP:P17898 PID:1302068 percent identity: 30.08; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
   
 0.608
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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