STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0731Conserved hypothetical protein; Similar to PID:1652491 percent identity: 36.19; identified by sequence similarity; putative; Belongs to the Nudix hydrolase family. (236 aa)    
Predicted Functional Partners:
TP_0805
Exoribonuclease II (rnb); Similar to PID:1652280 percent identity: 30.83; identified by sequence similarity; putative.
   
 0.998
TP_0770
ATP-dependent RNA helicase; Similar to GB:AE000782 percent identity: 50.14; identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
  
 0.990
TP_1029
Predicted coding region TP1029; Hypothetical protein; identified by Glimmer; putative.
  
 0.990
nadE
NH(3)-dependent NAD(+) synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.
   
 0.972
prs
Phosphoribosyl pyrophosphate synthetase (prs); Similar to GB:AE000783 percent identity: 44.86; identified by sequence similarity; putative; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 
 0.944
TP_0413
Phosphoglucomutase; Similar to GB:AE000783 percent identity: 35.60; identified by sequence similarity; putative.
    
  0.927
TP_0642
Phosphomannomutase (manB); Similar to GB:M34393 SP:P18159 PID:142994 PID:2226139 GB:AL009126 percent identity: 41.55; identified by sequence similarity; putative.
    
  0.927
TP_0485
Adenylate cyclase; Similar to GP:1754638 percent identity: 40.99; identified by sequence similarity; putative.
    
 0.840
pyrG
CTP synthase (pyrG); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
 0.797
pgsA2
Conserved hypothetical protein; Similar to PID:2088865 percent identity: 28.12; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.748
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.