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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltDGlutamate synthase (gltA); Similar to GP:2244618 percent identity: 48.79; identified by sequence similarity; putative. (518 aa)    
Predicted Functional Partners:
TP_0736
Hydrogenase, gamma chain (hydG); Similar to GB:L77117 PID:1592091 percent identity: 36.32; identified by sequence similarity; putative.
 0.999
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
  
 
 0.988
glmS
Glucosamine-fructose-6-phosphate aminotransferase (glmS); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.946
oadA
Oxaloacetate decarboxylase, subunit alpha (oadA); Similar to GB:J03885 SP:P13187 PID:149289 percent identity: 50.93; identified by sequence similarity; putative.
    
 0.933
proA
Glutamate-5-semialdehyde dehydrogenase (proA); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.929
gltX
glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
    
 0.924
nadE
NH(3)-dependent NAD(+) synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.
  
 0.871
TP_0223
Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative.
  
 
 0.859
deoD
Purine nucleoside phosphorylase (deoD); Similar to GP:1638807 percent identity: 57.51; identified by sequence similarity; putative.
    
 0.838
rnfC
Nitrogen fixation protein (rnfC); Similar to GB:X72888 GB:X79064 PID:435525 PID:483572 PID:1905810 percent identity: 27.00; identified by sequence similarity; putative.
 
  
 0.747
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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