STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0764Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 24.58; identified by sequence similarity; putative. (391 aa)    
Predicted Functional Partners:
TP_0981
Sensory transduction histidine kinase, putative; Similar to PID:1652841 percent identity: 33.93; identified by sequence similarity; putative.
  
 0.916
TP_0485
Adenylate cyclase; Similar to GP:1754638 percent identity: 40.99; identified by sequence similarity; putative.
    
  0.832
TP_0763
Predicted coding region TP0763; Hypothetical protein; identified by Glimmer; putative.
       0.686
TP_0261
Catabolite gene activator, putative; Similar to PID:1653345 percent identity: 30.99; identified by sequence similarity; putative.
    
  0.636
pth
peptidyl-tRNA hydrolase (pth); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
   
 
 0.557
TP_0172
Predicted coding region TP0172; Hypothetical protein; identified by Glimmer; putative.
   
 
 0.535
rpoE
RNA polymerase sigma-24 factor (rpoE); Similar to PID:699142 percent identity: 27.89; identified by sequence similarity; putative.
    
 
 0.509
TP_0073
Predicted coding region TP0073; Hypothetical protein; identified by Glimmer; putative.
 
   0.505
rpoN
RNA polymerase sigma-54 factor (rpoN); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
 
 0.498
TP_0104
5'-nucleotidase (ushA); Similar to GB:L42023 SP:P44569 PID:1003311 PID:1222124 PID:1204463 percent identity: 50.63; identified by sequence similarity; putative.
 
 
   0.494
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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