STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
htrA1Periplasmic serine protease DO (htrA-1); Similar to GB:L42023 SP:P45129 PID:1007190 PID:1221388 PID:1205500 percent identity: 39.19; identified by sequence similarity; putative. (398 aa)    
Predicted Functional Partners:
TP_0468
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 28.43; identified by sequence similarity; putative.
   
 0.894
flgG2
Flagellar basal-body rod protein (flgG-2); Similar to GB:AE000783 percent identity: 50.37; identified by sequence similarity; putative.
    
   0.761
rplK
Ribosomal protein L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.704
TP_0502
Predicted coding region TP0502; Hypothetical protein; identified by Glimmer; putative.
  
  0.657
TP_0835
Ankyrin, putative; Similar to GB:X56958 SP:Q01485 PID:29491 percent identity: 30.66; identified by sequence similarity; putative.
  
  0.657
TP_0261
Catabolite gene activator, putative; Similar to PID:1653345 percent identity: 30.99; identified by sequence similarity; putative.
   
 0.629
rpsF
Ribosomal protein S6 (rpsF); Binds together with S18 to 16S ribosomal RNA.
   
 
 0.620
TP_0920
Predicted coding region TP0920; Hypothetical protein; identified by Glimmer; putative.
   
  0.614
rplC
Ribosomal protein L3 (rplC); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
    
  0.611
rpsI
Ribosomal protein S9 (rpsI); Similar to SP:P07842 percent identity: 54.47; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS9 family.
   
   0.596
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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