| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| TP_0939 | mutL | TP_0939 | TP_0303 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | 0.708 |
| TP_0939 | nth | TP_0939 | TP_0775 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | Endonuclease III (nth); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.653 |
| TP_0939 | polA | TP_0939 | TP_0105 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.475 |
| coaE | nth | TP_0296 | TP_0775 | Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Endonuclease III (nth); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.568 |
| coaE | polA | TP_0296 | TP_0105 | Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.792 |
| fliY | nth | TP_0720 | TP_0775 | Flagellar motor switch protein (fliY); FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family. | Endonuclease III (nth); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.645 |
| mgtC | nth | TP_0774 | TP_0775 | Mg2+ transport protein (mgtC); Similar to PID:1001492 PID:1001567 percent identity: 48.39; identified by sequence similarity; putative. | Endonuclease III (nth); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.564 |
| mutL | TP_0939 | TP_0303 | TP_0939 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | 0.708 |
| mutL | mutY | TP_0303 | TP_0343 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | A/G-specific adenine glycosylase, putative; Similar to GB:AE000511 PID:2313226 percent identity: 38.92; identified by sequence similarity; putative. | 0.452 |
| mutL | nth | TP_0303 | TP_0775 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | Endonuclease III (nth); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.674 |
| mutL | polA | TP_0303 | TP_0105 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
| mutL | trcF | TP_0303 | TP_0344 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | Transcription-repair coupling factor (trcF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.584 |
| mutL | uvrC | TP_0303 | TP_0472 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | Excinuclease ABC, subunit C (uvrC); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.742 |
| mutL | xthA | TP_0303 | TP_0125 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | Exodeoxyribonuclease (exoA); Similar to GB:AE000666 percent identity: 53.36; identified by sequence similarity; putative. | 0.423 |
| mutY | mutL | TP_0343 | TP_0303 | A/G-specific adenine glycosylase, putative; Similar to GB:AE000511 PID:2313226 percent identity: 38.92; identified by sequence similarity; putative. | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | 0.452 |
| mutY | nth | TP_0343 | TP_0775 | A/G-specific adenine glycosylase, putative; Similar to GB:AE000511 PID:2313226 percent identity: 38.92; identified by sequence similarity; putative. | Endonuclease III (nth); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.788 |
| mutY | polA | TP_0343 | TP_0105 | A/G-specific adenine glycosylase, putative; Similar to GB:AE000511 PID:2313226 percent identity: 38.92; identified by sequence similarity; putative. | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.557 |
| mutY | trcF | TP_0343 | TP_0344 | A/G-specific adenine glycosylase, putative; Similar to GB:AE000511 PID:2313226 percent identity: 38.92; identified by sequence similarity; putative. | Transcription-repair coupling factor (trcF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.432 |
| mutY | uvrC | TP_0343 | TP_0472 | A/G-specific adenine glycosylase, putative; Similar to GB:AE000511 PID:2313226 percent identity: 38.92; identified by sequence similarity; putative. | Excinuclease ABC, subunit C (uvrC); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.745 |
| mutY | xthA | TP_0343 | TP_0125 | A/G-specific adenine glycosylase, putative; Similar to GB:AE000511 PID:2313226 percent identity: 38.92; identified by sequence similarity; putative. | Exodeoxyribonuclease (exoA); Similar to GB:AE000666 percent identity: 53.36; identified by sequence similarity; putative. | 0.995 |