STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0776Conserved hypothetical protein; Similar to SP:P46846 PID:606348 GB:U00096 PID:1789818 percent identity: 25.13; identified by sequence similarity; putative. (258 aa)    
Predicted Functional Partners:
dprA
Smf protein (smf); Similar to PID:1165281 PID:1196312 PID:1234878 GB:AE000783 percent identity: 32.71; identified by sequence similarity; putative.
  
 
 0.884
flgC
Flagellar basal-body rod protein (flgC); Similar to GP:2105146 percent identity: 67.11; identified by sequence similarity; putative.
   
   0.820
apt
Adenine phosphoribosyltransferase (apt); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.800
nadE
NH(3)-dependent NAD(+) synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.
     
 0.782
comE
comE protein, putative; Similar to PID:1652202 percent identity: 27.72; identified by sequence similarity; putative.
  
  
 0.764
xerD1
Integrase/recombinase (codV); Similar to GB:AL009126 percent identity: 39.66; identified by sequence similarity; putative; Belongs to the 'phage' integrase family.
   
    0.764
xerD2
Integrase/recombinase (xprB); Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
   
    0.764
fliY
Flagellar motor switch protein (fliY); FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
 
    0.714
recQ
ATP-dependent DNA helicase, putative; Similar to GB:M87049 SP:P15043 GB:M30198 PID:147559 PID:148221 percent identity: 38.81; identified by sequence similarity; putative.
     
  0.690
TP_0567
Conserved hypothetical protein; Similar to PID:1165270 PID:1196323 GB:AE000783 percent identity: 30.48; identified by sequence similarity; putative.
   
    0.654
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.