STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mazGmazG protein (mazG); Similar to GB:J04039 SP:P33646 PID:416198 PID:882675 GB:U00096 percent identity: 37.45; identified by sequence similarity; putative. (303 aa)    
Predicted Functional Partners:
nadE
NH(3)-dependent NAD(+) synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.
    
  0.970
TP_0485
Adenylate cyclase; Similar to GP:1754638 percent identity: 40.99; identified by sequence similarity; putative.
    
  0.941
TP_0920
Predicted coding region TP0920; Hypothetical protein; identified by Glimmer; putative.
    
  0.908
TP_0468
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 28.43; identified by sequence similarity; putative.
    
  0.907
TP_0261
Catabolite gene activator, putative; Similar to PID:1653345 percent identity: 30.99; identified by sequence similarity; putative.
    
  0.899
pyrG
CTP synthase (pyrG); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
    
  0.881
tmk
Thymidylate kinase (tmk); Similar to GB:L77117 SP:Q57741 PID:1591015 percent identity: 35.14; identified by sequence similarity; putative.
    
  0.881
coaE
Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
    
  0.870
apt
Adenine phosphoribosyltransferase (apt); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
  0.860
TP_0104
5'-nucleotidase (ushA); Similar to GB:L42023 SP:P44569 PID:1003311 PID:1222124 PID:1204463 percent identity: 50.63; identified by sequence similarity; putative.
 
  
  0.859
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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