STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0786ABC transporter, ATP-binding protein, putative; Similar to GB:D12938 SP:P31220 PID:285780 PID:551337 PID:606140 percent identity: 52.52; identified by sequence similarity; putative. (237 aa)    
Predicted Functional Partners:
TP_0883
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 19.26; identified by sequence similarity; putative.
 
 
 0.999
TP_0884
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 30.66; identified by sequence similarity; putative.
 
 
 0.999
TP_0785
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.37; identified by sequence similarity; putative.
  
  
 0.981
TP_0515
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 24.85; identified by sequence similarity; putative.
  
 
 0.838
tp92
Outer membrane protein; Might be part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane; Belongs to the BamA family.
 
  
 0.812
TP_0784
Predicted coding region TP0784; Hypothetical protein; identified by Glimmer; putative.
     
 0.779
cmk
Ribosomal protein S1 (rpsA); Similar to SP:P02349 GB:V00342 GB:V00352 GB:X04864 PID:42837 percent identity: 36.77; identified by sequence similarity; putative.
 
     0.612
rlpA
Rare lipoprotein A, putative; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
 
 
   0.532
rpoZ
DNA-directed RNA polymerase, putative; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
  
   0.452
lepA
GTP-binding membrane protein (lepA); Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.447
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.