STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0838ABC transporter, ATP-binding protein; Similar to PID:1027507 GB:AE000783 percent identity: 58.04; identified by sequence similarity; putative. (554 aa)    
Predicted Functional Partners:
rplD
Ribosomal protein L4 (rplD); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
 
 0.894
rplT
Ribosomal protein L20 (rplT); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity).
   
 
 0.891
rpmA
Ribosomal protein L27 (rpl27); Similar to PID:1653447 percent identity: 62.96; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.883
rplU
Ribosomal protein L21 (rplU); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
   0.882
rpsC
Ribosomal protein S3 (rpsC); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
   0.879
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.878
rpsO
Ribosomal protein S15 (rpsO); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
   0.878
rpmH
Ribosomal protein L34 (rpmH); Similar to SP:P29220 PID:454042 GB:AE000783 percent identity: 82.35; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL34 family.
   
   0.877
rplC
Ribosomal protein L3 (rplC); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.875
rpmC
Ribosomal protein L29 (rpmC); Similar to SP:P04457 percent identity: 30.36; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uL29 family.
    
 
 0.875
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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