STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0877Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.09; identified by sequence similarity; putative. (365 aa)    
Predicted Functional Partners:
TP_0981
Sensory transduction histidine kinase, putative; Similar to PID:1652841 percent identity: 33.93; identified by sequence similarity; putative.
 
 0.979
TP_0485
Adenylate cyclase; Similar to GP:1754638 percent identity: 40.99; identified by sequence similarity; putative.
 
  
  0.856
TP_0876
Conserved hypothetical protein; Similar to GB:U00096 SP:P76256 PID:1736440 PID:1736446 PID:1788109 percent identity: 32.58; identified by sequence similarity; putative.
     
 0.838
cheR
Chemotaxis protein methyltransferase (cheR); Similar to GB:AE000783 percent identity: 47.10; identified by sequence similarity; putative.
   
   0.770
flgG2
Flagellar basal-body rod protein (flgG-2); Similar to GB:AE000783 percent identity: 50.37; identified by sequence similarity; putative.
    
   0.769
tsaE
Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
       0.639
TP_0261
Catabolite gene activator, putative; Similar to PID:1653345 percent identity: 30.99; identified by sequence similarity; putative.
    
  0.636
fliD
Flagellar filament cap protein (fliD); Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
     
 0.542
TP_0873
Predicted coding region TP0873; Hypothetical protein; identified by Glimmer; putative.
       0.523
TP_0874
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 35.37; identified by sequence similarity; putative.
       0.523
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.