STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0883Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 19.26; identified by sequence similarity; putative. (365 aa)    
Predicted Functional Partners:
TP_0786
ABC transporter, ATP-binding protein, putative; Similar to GB:D12938 SP:P31220 PID:285780 PID:551337 PID:606140 percent identity: 52.52; identified by sequence similarity; putative.
 
 
 0.999
TP_0884
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 30.66; identified by sequence similarity; putative.
 
  
 0.998
TP_0882
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 25.68; identified by sequence similarity; putative.
       0.835
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.746
pnp
Polyribonucleotide nucleotidyltransferase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
       0.746
TP_0515
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 24.85; identified by sequence similarity; putative.
  
 
 0.742
TP_0785
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.37; identified by sequence similarity; putative.
     
 0.652
rpsO
Ribosomal protein S15 (rpsO); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
       0.561
TP_0878
Predicted coding region TP0878; Hypothetical protein; identified by Glimmer; putative.
       0.559
TP_0879
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 26.00; identified by sequence similarity; putative.
       0.559
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.