STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0884Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 30.66; identified by sequence similarity; putative. (362 aa)    
Predicted Functional Partners:
TP_0786
ABC transporter, ATP-binding protein, putative; Similar to GB:D12938 SP:P31220 PID:285780 PID:551337 PID:606140 percent identity: 52.52; identified by sequence similarity; putative.
 
 
 0.999
TP_0883
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 19.26; identified by sequence similarity; putative.
 
  
 0.998
TP_0882
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 25.68; identified by sequence similarity; putative.
       0.805
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.771
pnp
Polyribonucleotide nucleotidyltransferase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
       0.771
TP_0515
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 24.85; identified by sequence similarity; putative.
  
 
 0.742
TP_0785
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.37; identified by sequence similarity; putative.
     
 0.652
tp92
Outer membrane protein; Might be part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane; Belongs to the BamA family.
 
     0.625
lnt2
Apolipoprotein N-acyltransferase (cutE); Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.
 
    0.599
TP_0879
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 26.00; identified by sequence similarity; putative.
 
     0.589
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.