STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rplSRibosomal protein L19 (rplS); This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (123 aa)    
Predicted Functional Partners:
rpsP
Ribosomal protein S16 (rpsP); Similar to SP:P21474 PID:2309081 GB:AL009126 percent identity: 53.85; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bS16 family.
 
 
 0.998
trmD
tRNA (guanine-N1)-methyltransferase (trmD); Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
 
  
 0.996
rplK
Ribosomal protein L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 0.995
rplA
Ribosomal protein L1 (rplA); Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
 
 0.995
cmk
Ribosomal protein S1 (rpsA); Similar to SP:P02349 GB:V00342 GB:V00352 GB:X04864 PID:42837 percent identity: 36.77; identified by sequence similarity; putative.
  
 
 0.995
rpmB
Ribosomal protein L28 (rpmB); Similar to GP:1763103 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL28 family.
  
 
 0.995
rpsB
Ribosomal protein S2 (rpsB); Similar to GB:AE000783 percent identity: 58.75; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.995
rpmA
Ribosomal protein L27 (rpl27); Similar to PID:1653447 percent identity: 62.96; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.995
rplU
Ribosomal protein L21 (rplU); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 0.995
rpsU
Ribosomal protein S21 (rpsU); Similar to SP:P49225 PID:710340 percent identity: 52.54; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bS21 family.
  
 
 0.995
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.