STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mgtEMg2+ transport protein (mgtE); Acts as a magnesium transporter. (449 aa)    
Predicted Functional Partners:
TP_0916
Predicted coding region TP0916; Hypothetical protein; identified by Glimmer; putative.
       0.773
TP_0918
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 25.71; identified by sequence similarity; putative.
       0.737
TP_0567
Conserved hypothetical protein; Similar to PID:1165270 PID:1196323 GB:AE000783 percent identity: 30.48; identified by sequence similarity; putative.
    
 
 0.736
TP_0104
5'-nucleotidase (ushA); Similar to GB:L42023 SP:P44569 PID:1003311 PID:1222124 PID:1204463 percent identity: 50.63; identified by sequence similarity; putative.
    
  0.728
lolE1
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 30.77; identified by sequence similarity; putative.
      
 0.613
TP_0438
Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.612
TP_0915
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 26.71; identified by sequence similarity; putative.
       0.598
apt
Adenine phosphoribosyltransferase (apt); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.590
TP_1034
Conserved hypothetical integral membrane protein; Similar to SP:P45394 PID:606134 GB:U00096 PID:1789587 percent identity: 33.02; identified by sequence similarity; putative.
   
   0.536
TP_0055
Predicted coding region TP0055; Hypothetical protein; identified by Glimmer; putative.
   
   0.517
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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