STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
texTex protein (tex); Similar to GP:1477402 percent identity: 40.97; identified by sequence similarity; putative. (778 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.945
rpoB
DNA-directed RNA polymerase, beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.940
rpoZ
DNA-directed RNA polymerase, putative; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
    
  0.930
TP_0261
Catabolite gene activator, putative; Similar to PID:1653345 percent identity: 30.99; identified by sequence similarity; putative.
   
 
 0.522
TP_0017
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 36.16; identified by sequence similarity; putative.
    
   0.509
TP_0067
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 47.91; identified by sequence similarity; putative.
    
   0.509
TP_0268
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 28.74; identified by sequence similarity; putative.
    
   0.509
TP_0468
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 28.43; identified by sequence similarity; putative.
    
   0.509
TP_0820
Hypothetical protein; Similar to GP:2196997 percent identity: 99.61; identified by sequence similarity; putative.
    
   0.509
TP_0954
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 24.29; identified by sequence similarity; putative.
    
   0.509
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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