STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliSFlagellar protein (fliS); Similar to GB:Z31376 SP:P39739 PID:499382 PID:1762346 GB:AL009126 percent identity: 34.48; identified by sequence similarity; putative. (148 aa)    
Predicted Functional Partners:
flaB3
Flagellar filament 31 kDa core protein (flaB3); Component of the core of the flagella.
 
 
 0.997
flhA
Flagellar biosynthesis protein (flhA); Involved in the export of flagellum proteins; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
  
 
 0.996
fliY
Flagellar motor switch protein (fliY); FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
 
  
 0.996
cheW1
Purine-binding chemotaxis protein (cheW-1); Similar to GP:1765974 percent identity: 99.78; identified by sequence similarity; putative.
  
  
 0.994
flgL
Flagellar hook-associated protein 3 (flgL); Similar to GP:1518047 percent identity: 29.50; identified by sequence similarity; putative.
 
 
 0.994
flaB2
Flagellar filament 33 kDa core protein (flaB2); Component of the core of the flagella.
 
 
 0.994
flaB1
Flagellar filament 34.5 kDa core protein (flaB1); Component of the core of the flagella.
 
 
 0.994
flgK
Flagellar hook-associated protein 1 (flgK); Similar to SP:P70859 PID:1518046 GB:AE000783 percent identity: 39.78; identified by sequence similarity; putative.
 
 
 0.993
TP_0974
Predicted coding region TP0974; Hypothetical protein; identified by Glimmer; putative.
  
 
 0.992
fliD
Flagellar filament cap protein (fliD); Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
 
 
 0.980
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.