STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0962Conserved hypothetical integral membrane protein; Similar to GB:AL009126 percent identity: 28.89; identified by sequence similarity; putative. (410 aa)    
Predicted Functional Partners:
TP_0964
ABC transporter, ATP-binding protein; Similar to GB:AL009126 percent identity: 49.32; identified by sequence similarity; putative.
 0.998
lolD
ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
 0.989
TP_0963
Conserved hypothetical integral membrane protein; Similar to GB:AL009126 percent identity: 31.84; identified by sequence similarity; putative.
 
  
0.960
macA
Membrane fusion protein, putative; Similar to GB:L42023 PID:1005989 PID:1220998 PID:1205141 SP:Q57500 percent identity: 25.88; identified by sequence similarity; putative.
 
 
 0.947
metN
Amino acid ABC transporter, ATP-binding protein (abc); Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
 
    
 0.727
TP_0959
Predicted coding region TP0959; Hypothetical protein; identified by Glimmer; putative.
     
 0.549
cbiO
Cobalt ABC transporter, ATP-binding protein; Similar to GB:L77117 PID:1591732 percent identity: 37.91; identified by sequence similarity; putative.
 
      0.548
flgG2
Flagellar basal-body rod protein (flgG-2); Similar to GB:AE000783 percent identity: 50.37; identified by sequence similarity; putative.
       0.548
TP_0966
Predicted coding region TP0966; Hypothetical protein; identified by Glimmer; putative; Belongs to the TP096X family.
     
 0.543
msrAB
protein-methionine-S-oxide reductase (msrA); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
     
 0.500
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.