STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0964ABC transporter, ATP-binding protein; Similar to GB:AL009126 percent identity: 49.32; identified by sequence similarity; putative. (235 aa)    
Predicted Functional Partners:
TP_0963
Conserved hypothetical integral membrane protein; Similar to GB:AL009126 percent identity: 31.84; identified by sequence similarity; putative.
 0.999
TP_0962
Conserved hypothetical integral membrane protein; Similar to GB:AL009126 percent identity: 28.89; identified by sequence similarity; putative.
 0.998
macA
Membrane fusion protein, putative; Similar to GB:L42023 PID:1005989 PID:1220998 PID:1205141 SP:Q57500 percent identity: 25.88; identified by sequence similarity; putative.
 
 
 0.972
lolE2
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 23.27; identified by sequence similarity; putative.
 
 0.957
lolE1
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 30.77; identified by sequence similarity; putative.
  
 0.952
lolD
ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
  
0.874
TP_0966
Predicted coding region TP0966; Hypothetical protein; identified by Glimmer; putative; Belongs to the TP096X family.
     
 0.742
msrAB
protein-methionine-S-oxide reductase (msrA); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
     
 0.678
TP_0333
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.40; identified by sequence similarity; putative.
   
 
 0.673
TP_0789
Predicted coding region TP0789; Hypothetical protein; identified by Glimmer; putative.
   
 
 0.673
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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