STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macAMembrane fusion protein, putative; Similar to GB:L42023 PID:1005989 PID:1220998 PID:1205141 SP:Q57500 percent identity: 25.88; identified by sequence similarity; putative. (320 aa)    
Predicted Functional Partners:
TP_0963
Conserved hypothetical integral membrane protein; Similar to GB:AL009126 percent identity: 31.84; identified by sequence similarity; putative.
 
 
 0.997
TP_0964
ABC transporter, ATP-binding protein; Similar to GB:AL009126 percent identity: 49.32; identified by sequence similarity; putative.
 
 
 0.995
TP_0962
Conserved hypothetical integral membrane protein; Similar to GB:AL009126 percent identity: 28.89; identified by sequence similarity; putative.
 
 
 0.991
lolD
ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
 
 0.969
norM
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 24.31; identified by sequence similarity; putative.
      
 0.716
TP_0966
Predicted coding region TP0966; Hypothetical protein; identified by Glimmer; putative; Belongs to the TP096X family.
       0.703
TP_0959
Predicted coding region TP0959; Hypothetical protein; identified by Glimmer; putative.
 
   
 0.614
msrAB
protein-methionine-S-oxide reductase (msrA); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
     
 0.613
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
   
 
 0.577
TP_0967
Predicted coding region TP0967; Hypothetical protein; identified by Glimmer; putative; Belongs to the TP096X family.
       0.575
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.