STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftr1Conserved hypothetical integral membrane protein; Similar to GB:X73124 SP:P39595 PID:413951 GB:AL009126 percent identity: 32.05; identified by sequence similarity; putative. (448 aa)    
Predicted Functional Partners:
tpd
Membrane antigen, pathogen-specific (tpd); This antigen is a pathogen-specific membrane immunogen; Belongs to the UPF0423 family.
 
  
 0.989
TP_0964
ABC transporter, ATP-binding protein; Similar to GB:AL009126 percent identity: 49.32; identified by sequence similarity; putative.
  
  
 0.628
TP_0959
Predicted coding region TP0959; Hypothetical protein; identified by Glimmer; putative.
 
   
 0.609
TP_0963
Conserved hypothetical integral membrane protein; Similar to GB:AL009126 percent identity: 31.84; identified by sequence similarity; putative.
  
  
 0.579
TP_0962
Conserved hypothetical integral membrane protein; Similar to GB:AL009126 percent identity: 28.89; identified by sequence similarity; putative.
  
  
 0.549
pheS
phenylalanyl-tRNA synthetase alpha subunit (pheS); Similar to SP:P94282 PID:1785607 GB:AE000783 percent identity: 49.61; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
       0.549
troR
Cation-activated repressor protein (troR); Similar to GP:1777937 percent identity: 100.00; identified by sequence similarity; putative.
     
 0.533
macA
Membrane fusion protein, putative; Similar to GB:L42023 PID:1005989 PID:1220998 PID:1205141 SP:Q57500 percent identity: 25.88; identified by sequence similarity; putative.
  
  
 0.505
TP_0143
Thiamine ABC transporter, permease protein, putative; Similar to PID:1098688 percent identity: 26.02; identified by sequence similarity; putative.
   
  
 0.449
TP_0969
Predicted coding region TP0969; Hypothetical protein; identified by Glimmer; putative; Belongs to the TP096X family.
     
 0.410
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.