STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0976Predicted coding region TP0976; Hypothetical protein; identified by Glimmer; putative. (459 aa)    
Predicted Functional Partners:
TP_0977
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 44.30; identified by sequence similarity; putative.
       0.781
lspA
Signal peptidase II (lsp); This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
       0.774
rsmI
Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.561
tatD1
Conserved hypothetical protein; Similar to GB:L42023 SP:P44718 PID:1003792 PID:1222386 PID:1204704 percent identity: 36.17; identified by sequence similarity; putative.
       0.461
dus
Histidine phosphokinase/phophatase (ntrB); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family.
       0.461
TP_0974
Predicted coding region TP0974; Hypothetical protein; identified by Glimmer; putative.
       0.455
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.