STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tatD1Conserved hypothetical protein; Similar to GB:L42023 SP:P44718 PID:1003792 PID:1222386 PID:1204704 percent identity: 36.17; identified by sequence similarity; putative. (257 aa)    
Predicted Functional Partners:
dus
Histidine phosphokinase/phophatase (ntrB); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family.
       0.852
fliE
Flagellar hook-basal body complex protein (fliE); Similar to GP:2105147 percent identity: 58.12; identified by sequence similarity; putative.
    
 
 0.819
metG
methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.696
TP_0981
Sensory transduction histidine kinase, putative; Similar to PID:1652841 percent identity: 33.93; identified by sequence similarity; putative.
       0.592
mltG
Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
      0.563
TP_0982
glpG protein, putative; Similar to GP:606359 percent identity: 29.47; identified by sequence similarity; putative.
       0.562
TP_0983
Predicted coding region TP0983; Hypothetical protein; identified by Glimmer; putative.
       0.562
lspA
Signal peptidase II (lsp); This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
       0.509
ssb
Single-strand DNA binding protein (ssb); Similar to GB:AE000783 percent identity: 48.15; identified by sequence similarity; putative.
  
    0.481
ssb2
Predicted coding region TP0310; Hypothetical protein; identified by Glimmer; putative.
  
    0.481
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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