Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TP_0991Rubredoxin; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule (By similarity). (52 aa)    
Predicted Functional Partners:
sorA
Desulfoferrodoxin (rbo); Similar to GB:M81168 SP:P20418 GB:M28848 PID:145115 PID:758676 percent identity: 44.04; identified by sequence similarity; putative.
  
  
 0.872
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
    
 0.849
TP_0992
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.40; identified by sequence similarity; putative.
       0.665
ahpC
Alkyl hydroperoxide reductase (ahpC); Similar to PID:1064782 GB:AL009126 percent identity: 48.92; identified by sequence similarity; putative.
  
  
 0.663
TP_0990
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 23.34; identified by sequence similarity; putative.
       0.584
trxA
Thioredoxin (trx); Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
  
  
 0.557
msrAB
protein-methionine-S-oxide reductase (msrA); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
     
 0.532
rimM
Conserved hypothetical protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
    
 
 0.489
TP_0989
P26; Similar to GB:AE000783 percent identity: 31.90; identified by sequence similarity; putative.
       0.434
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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