STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlpARare lipoprotein A, putative; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (318 aa)    
Predicted Functional Partners:
TP_0304
Predicted coding region TP0304; Hypothetical protein; identified by Glimmer; putative.
  
 
 0.775
proA
Glutamate-5-semialdehyde dehydrogenase (proA); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
   
 
 0.721
TP_0623
Membrane-bound lytic murein transglycosylase D (dniR); Similar to SP:P23931 GB:X60739 PID:1208972 PID:581068 GB:U00096 percent identity: 32.28; identified by sequence similarity; putative.
  
  
 0.710
amiC
N-acetylmuramoyl-L-alanine amidase (amiA); Similar to SP:P36548 GB:X75413 PID:453968 GB:U00096 PID:1788776 percent identity: 30.74; identified by sequence similarity; putative.
 
 
 0.687
metG
methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
   0.593
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
   
   0.584
TP_0282
Predicted coding region TP0282; Hypothetical protein; identified by Glimmer; putative.
   
 
 0.568
ftsA
Cell division protein (ftsA); Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
  
 
 0.561
TP_0688
Immunity protein (mccF); Similar to GP:1732242 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the peptidase S66 family.
   
 
 0.546
pbp1
Penicillin-binding protein (pbp-1); Similar to GB:AE000783 percent identity: 37.14; identified by sequence similarity; putative.
   
 
 0.530
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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