close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_1002Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.50; identified by sequence similarity; putative. (222 aa)    
Predicted Functional Partners:
TP_0989
P26; Similar to GB:AE000783 percent identity: 31.90; identified by sequence similarity; putative.
  
 
   0.853
TP_0990
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 23.34; identified by sequence similarity; putative.
  
     0.774
TP_0408
Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative.
  
     0.773
TP_0496
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 29.52; identified by sequence similarity; putative.
  
     0.771
TP_0333
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.40; identified by sequence similarity; putative.
  
     0.770
TP_0392
Conserved hypothetical protein; Similar to PID:1165282 PID:1196311 PID:1234877 GB:AE000783 percent identity: 24.15; identified by sequence similarity; putative.
  
     0.770
TP_0263
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 24.22; identified by sequence similarity; putative.
  
     0.768
TP_0996
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 30.00; identified by sequence similarity; putative.
  
     0.766
TP_0522
Predicted coding region TP0522; Hypothetical protein; identified by Glimmer; putative.
  
     0.761
TP_0739
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 25.32; identified by sequence similarity; putative.
  
     0.760
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (18%) [HD]