| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| TP_0939 | pgk | TP_0939 | TP_0538 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | Phosphoglycerate kinase (pgk); Similar to GB:L32595 PID:483399 SP:Q59181 PID:1314258 GB:AE000783 percent identity: 48.99; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family. | 0.870 |
| TP_0939 | pgl | TP_0939 | TP_0477 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | Glucose-6-phosphate 1-dehydrogenase, putative; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 0.933 |
| TP_0939 | secA | TP_0939 | TP_0379 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | Preprotein translocase subunit (secA); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.884 |
| TP_0939 | topA | TP_0939 | TP_0394 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | 0.973 |
| TP_0939 | trxA | TP_0939 | TP_0919 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | Thioredoxin (trx); Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. | 0.880 |
| TP_0939 | zntA | TP_0939 | TP_1036 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | Cation-transporting ATPase, P-type; Similar to GB:AE000782 percent identity: 38.53; identified by sequence similarity; putative. | 0.817 |
| mtnN | zntA | TP_0170 | TP_1036 | Pfs protein (pfs); Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Cation-transporting ATPase, P-type; Similar to GB:AE000782 percent identity: 38.53; identified by sequence similarity; putative. | 0.472 |
| murJ | secA | TP_0516 | TP_0379 | Virulence factor (mviN); Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | Preprotein translocase subunit (secA); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.685 |
| murJ | zntA | TP_0516 | TP_1036 | Virulence factor (mviN); Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | Cation-transporting ATPase, P-type; Similar to GB:AE000782 percent identity: 38.53; identified by sequence similarity; putative. | 0.648 |
| pgk | TP_0939 | TP_0538 | TP_0939 | Phosphoglycerate kinase (pgk); Similar to GB:L32595 PID:483399 SP:Q59181 PID:1314258 GB:AE000783 percent identity: 48.99; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family. | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | 0.870 |
| pgk | trxA | TP_0538 | TP_0919 | Phosphoglycerate kinase (pgk); Similar to GB:L32595 PID:483399 SP:Q59181 PID:1314258 GB:AE000783 percent identity: 48.99; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family. | Thioredoxin (trx); Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. | 0.510 |
| pgk | zntA | TP_0538 | TP_1036 | Phosphoglycerate kinase (pgk); Similar to GB:L32595 PID:483399 SP:Q59181 PID:1314258 GB:AE000783 percent identity: 48.99; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family. | Cation-transporting ATPase, P-type; Similar to GB:AE000782 percent identity: 38.53; identified by sequence similarity; putative. | 0.468 |
| pgl | TP_0939 | TP_0477 | TP_0939 | Glucose-6-phosphate 1-dehydrogenase, putative; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | 0.933 |
| pgl | zntA | TP_0477 | TP_1036 | Glucose-6-phosphate 1-dehydrogenase, putative; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | Cation-transporting ATPase, P-type; Similar to GB:AE000782 percent identity: 38.53; identified by sequence similarity; putative. | 0.516 |
| secA | TP_0939 | TP_0379 | TP_0939 | Preprotein translocase subunit (secA); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | 0.884 |
| secA | murJ | TP_0379 | TP_0516 | Preprotein translocase subunit (secA); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Virulence factor (mviN); Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.685 |
| secA | topA | TP_0379 | TP_0394 | Preprotein translocase subunit (secA); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | 0.554 |
| secA | trxA | TP_0379 | TP_0919 | Preprotein translocase subunit (secA); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Thioredoxin (trx); Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. | 0.523 |
| secA | zntA | TP_0379 | TP_1036 | Preprotein translocase subunit (secA); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Cation-transporting ATPase, P-type; Similar to GB:AE000782 percent identity: 38.53; identified by sequence similarity; putative. | 0.632 |
| topA | TP_0939 | TP_0394 | TP_0939 | DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | 0.973 |