STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysS2lysyl-tRNA synthetase (lysS-2); Similar to GB:U14003 SP:P03812 GB:J01611 GB:X59988 PID:41552 percent identity: 34.30; identified by sequence similarity; putative. (351 aa)    
Predicted Functional Partners:
efp
Translation elongation factor P (efp); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
   
 
 0.959
clpP2
ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
       0.773
TP_0121
Conserved hypothetical protein; Similar to GB:L42023 SP:P44641 PID:1003549 PID:1222253 PID:1204581 percent identity: 30.37; identified by sequence similarity; putative; Belongs to the radical SAM superfamily. KamA family.
 
  
 0.696
TP_0025
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 32.52; identified by sequence similarity; putative.
   
   0.402
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.