| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| TP_0939 | clpP2 | TP_0939 | TP_1041 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.844 |
| TP_0939 | clpX | TP_0939 | TP_0508 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | ATP-dependent Clp protease subunit X (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.404 |
| TP_0939 | lon | TP_0939 | TP_0524 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.787 |
| TP_0939 | nifS | TP_0939 | TP_0863 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | Nitrogen fixation protein (nifS-2); Similar to GB:M86823 SP:Q01179 GB:U22347 PID:151968 percent identity: 38.19; identified by sequence similarity; putative. | 0.794 |
| TP_0939 | polA | TP_0939 | TP_0105 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.539 |
| TP_0939 | prs | TP_0939 | TP_0294 | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | Phosphoribosyl pyrophosphate synthetase (prs); Similar to GB:AE000783 percent identity: 44.86; identified by sequence similarity; putative; Belongs to the ribose-phosphate pyrophosphokinase family. | 0.738 |
| clpA1 | clpP2 | TP_0549 | TP_1041 | ATPase (clpC); Similar to GB:D26185 SP:P37571 GB:U02604 GB:X75930 PID:442360 percent identity: 44.35; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.851 |
| clpA1 | lon | TP_0549 | TP_0524 | ATPase (clpC); Similar to GB:D26185 SP:P37571 GB:U02604 GB:X75930 PID:442360 percent identity: 44.35; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.764 |
| clpA2 | clpP2 | TP_0801 | TP_1041 | ATP-dependent Clp protease subunit A (clpA); Similar to GB:M31045 SP:P15716 PID:145549 PID:499142 GB:U00096 percent identity: 48.63; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.857 |
| clpA2 | clpX | TP_0801 | TP_0508 | ATP-dependent Clp protease subunit A (clpA); Similar to GB:M31045 SP:P15716 PID:145549 PID:499142 GB:U00096 percent identity: 48.63; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease subunit X (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.583 |
| clpA2 | lon | TP_0801 | TP_0524 | ATP-dependent Clp protease subunit A (clpA); Similar to GB:M31045 SP:P15716 PID:145549 PID:499142 GB:U00096 percent identity: 48.63; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.764 |
| clpB | clpP2 | TP_0071 | TP_1041 | ATP-dependent Clp protease subunit B (clpB); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the ClpA [...] | ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.851 |
| clpB | lon | TP_0071 | TP_0524 | ATP-dependent Clp protease subunit B (clpB); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the ClpA [...] | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.764 |
| clpP2 | TP_0939 | TP_1041 | TP_0939 | ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative. | 0.844 |
| clpP2 | clpA1 | TP_1041 | TP_0549 | ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATPase (clpC); Similar to GB:D26185 SP:P37571 GB:U02604 GB:X75930 PID:442360 percent identity: 44.35; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | 0.851 |
| clpP2 | clpA2 | TP_1041 | TP_0801 | ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease subunit A (clpA); Similar to GB:M31045 SP:P15716 PID:145549 PID:499142 GB:U00096 percent identity: 48.63; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | 0.857 |
| clpP2 | clpB | TP_1041 | TP_0071 | ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease subunit B (clpB); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the ClpA [...] | 0.851 |
| clpP2 | clpX | TP_1041 | TP_0508 | ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease subunit X (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.992 |
| clpP2 | lon | TP_1041 | TP_0524 | ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.737 |
| clpP2 | lysS2 | TP_1041 | TP_1040 | ATP-dependent Clp protease proteolytic component (clpP-2); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | lysyl-tRNA synthetase (lysS-2); Similar to GB:U14003 SP:P03812 GB:J01611 GB:X59988 PID:41552 percent identity: 34.30; identified by sequence similarity; putative. | 0.773 |
