STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
VC_0019Valine-pyruvate aminotransferase; Similar to SP:P09053 PID:466710 GB:U00096 PID:1789996; identified by sequence similarity; putative. (418 aa)    
Predicted Functional Partners:
ilvE
Branched-chain amino acid amiotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.922
VC_1977
Aspartate aminotransferase, putative; Similar to GB:U00096 PID:1788627 PID:1799660; identified by sequence similarity; putative.
     
 0.912
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
     
 0.905
ilvD
Dihydroxy-acid dehydratase; Similar to GP:288532; identified by sequence similarity; putative; Belongs to the IlvD/Edd family.
     
 0.902
glyS
glycyl-tRNA synthetase, beta chain; Similar to SP:P00961 GB:J01622 PID:146223 PID:466697 GB:U00096; identified by sequence similarity; putative.
       0.679
glyQ
glycyl-tRNA synthetase, alpha chain; Similar to SP:P00960 GB:J01622 PID:146222 PID:146225 PID:466698; identified by sequence similarity; putative.
       0.673
bsrV
Alanine racemase, putative; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes ten of the 19 natural chiral amino acids known, including both non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Cys, Gln and Asn) and positively charged amino acids (His, Lys and Arg). Among these substrates, is the most efficient with lysine and arginine. Is also able to catalyze the racemization of several amino acids that are not typically incorporated into proteins such as ornithine and norleucine. Is not active on negatively charged (Glu and Asp) or aromati [...]
     
 0.599
alr1
Alanine racemase, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan. To a lesser extent, is also able to racemize L-serine and D-serine. Does not act on other proteinogenic amino-acids.
     
 0.582
VC_0153
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.474
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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