Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
VC_0042Potassium uptake protein TrkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. (481 aa)    
Predicted Functional Partners:
VC_0043
Potassium uptake protein TrkA; Similar to GB:D28477 SP:P39448 PID:541661; identified by sequence similarity; putative.
 
 
 0.992
VC_0041
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.849
VC_0992
Glutathione-regulated potassium-efflux system protein KefB, putative; Similar to SP:P52068 GB:U00096 PID:1773160 PID:1786685; identified by sequence similarity; putative; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.817
rsmB
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.816
VC_A0194
Potassium channel protein, putative; Similar to PID:1089906; identified by sequence similarity; putative.
  
 
 0.777
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
  
 0.758
def1
Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.723
VC_0050
DNA topoisomerase I-related protein; Similar to SP:P45771 PID:606217 GB:U00096 PID:1789677; identified by sequence similarity; putative.
     
 0.665
VC_0047
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.659
VC_0048
Smf protein; Similar to GB:L42023 SP:P43862 PID:1006171 PID:1221098 PID:609332; identified by sequence similarity; putative.
       0.659
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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