STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_0068Transcriptional regulator, LysR family; Similar to GB:L10328 SP:P31463 PID:290559 GB:U00096 PID:1790147; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family. (327 aa)    
Predicted Functional Partners:
VC_0069
Multidrug resistance protein, putative; Similar to GB:L10328 SP:P31462 PID:290558 GB:U00096 PID:1790146; identified by sequence similarity; putative.
       0.753
VC_0067
Similar to GP:2584787; identified by sequence similarity; putative.
       0.724
rpoS
RNA polymerase sigma-38 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response (By similarity). May be required for the persistence of V.cholerae in aquatic habitats.
    
 
 0.579
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
    
 
 0.577
VC_1410
Multidrug resistance protein VceA; Similar to GP:3378278; identified by sequence similarity; putative.
  
   
 0.574
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.570
VC_0070
Hypothetical protein; Identified by Glimmer2; putative.
       0.544
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.516
VC_0629
Multidrug resistance protein, putative; Similar to GB:U00096 PID:1736781 PID:1736784 PID:1788390 GB:U00096; identified by sequence similarity; putative; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.514
VC_0776
Ferric vibriobactin ABC transporter, periplasmic ferric vibriobactin-binding protein; Similar to GB:M29730 SP:P14609 GB:X53274 PID:145944 PID:581195; identified by sequence similarity; putative.
      
 0.514
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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