Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_0069Multidrug resistance protein, putative; Similar to GB:L10328 SP:P31462 PID:290558 GB:U00096 PID:1790146; identified by sequence similarity; putative. (400 aa)    
Predicted Functional Partners:
VC_0067
Similar to GP:2584787; identified by sequence similarity; putative.
     
 0.793
VC_0068
Transcriptional regulator, LysR family; Similar to GB:L10328 SP:P31463 PID:290559 GB:U00096 PID:1790147; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
       0.753
VC_0070
Hypothetical protein; Identified by Glimmer2; putative.
       0.737
VC_1391
Multidrug transporter, putative; Similar to GB:AL009126; identified by sequence similarity; putative.
  
   
 0.671
VC_1597
Multidrug transporter, putative; Similar to PID:1217600; identified by sequence similarity; putative.
  
   
 0.629
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits) (By similarity).
   
  
 0.571
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
      
 0.565
VC_1579
Enterobactin synthetase component F-related protein; Similar to GB:M60177 SP:P11454 GB:M17354 PID:145843 PID:551801; identified by sequence similarity; putative.
  
   
 0.419
tolC
Outer membrane protein TolC; Outer membrane channel, which is required for the function of several efflux systems (By similarity). Required to export RtxA cytotoxin; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
   
 
 0.410
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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