STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0071Transcriptional regulator AsnC; Similar to GB:L10328 SP:P03809 GB:K00826 PID:290592 PID:455179; identified by sequence similarity; putative. (153 aa)    
Predicted Functional Partners:
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
    
 0.792
birA
birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
 
 0.779
VC_1062
Transcriptional regulator, AsnC family; Similar to SP:P54986 GB:U00096 PID:1580718 PID:1773131 PID:1786652; identified by sequence similarity; putative.
  
     0.770
VC_1713
Transcriptional regulator, AsnC family; Similar to PID:1816639; identified by sequence similarity; putative.
  
     0.770
VC_0072
Sensory box/GGDEF family protein; Similar to PID:1651932; identified by sequence similarity; putative.
       0.606
rsmJ
Conserved hypothetical protein; Specifically methylates the guanosine in position 1516 of 16S rRNA.
       0.606
VC_2373
Glutamate synthase, large subunit; Similar to GB:X80485 PID:515938 SP:P55037 PID:1652093; identified by sequence similarity; putative.
     
 0.471
VC_2376
Glutamate synthase, large subunit; Similar to PID:606151 GB:U00096 PID:1789605; identified by sequence similarity; putative.
     
 0.471
VC_0074
Hypothetical protein; Identified by Glimmer2; putative.
       0.451
VC_A0574
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
  0.431
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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