Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ubiEUbiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (260 aa)    
Predicted Functional Partners:
VC_2475
ubiH protein; Similar to GB:D90281 SP:P25534 PID:216628 PID:882437 GB:U00096; identified by sequence similarity; putative.
  
 
 0.971
VC_0963
VisC-related protein; Similar to GB:U00096 PID:1778581 PID:1786883; identified by sequence similarity; putative.
  
 
 0.940
ubiB
Ubiquinone biosynthesis protein AarF, putative; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
 
  
 0.937
VC_0084
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.932
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 0.920
ubiG
3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.905
VC_0651
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.902
VC_0654
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.902
VC_0652
Protease, putative; Similar to SP:P45527 PID:606098 GB:U00096 PID:1789548; identified by sequence similarity; putative.
     
 0.900
VC_2166
Trp repressor-binding protein; Similar to GB:M99166 SP:P30849 PID:148264 GB:U00096 PID:1651499; identified by sequence similarity; putative.
     
  0.900
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (22%) [HD]