STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0090DNA-damage-inducible protein F; Similar to SP:P28303 PID:146611 PID:396379 GB:U00096 PID:1790477; identified by sequence similarity; putative. (454 aa)    
Predicted Functional Partners:
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.678
VC_0091
O-methyltransferase-related protein; Similar to GB:M80674 SP:P39887 PID:153491; identified by sequence similarity; putative.
       0.624
VC_1915
Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
  
    0.568
norM
Multidrug resistance protein NorM, putative; Multidrug efflux pump that functions as a Na(+)/drug antiporter. Confers resistance to norfloxacin, ciprofloxacin, ofloxacin, daunomycin, doxorubicin, streptomycin, kanamycin, ethidium bromide and acriflavine; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
  
   
 0.476
argG
Argininosuccinate synthase; Similar to GB:AL009126; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
 0.457
epd
D-erythrose 4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.
   
  
 0.455
VC_1069
Glyceraldehyde 3-phosphate dehydrogenase; Similar to GB:L07499 SP:P34918 PID:410113; identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.455
VC_2000
Glyceraldehyde 3-phosphate dehydrogenase; Similar to GB:X02662 SP:P06977 GB:M66870 GB:M66871 GB:M66872; identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.455
VC_A0843
Glyceraldehyde 3-phosphate dehydrogenase; Similar to GP:3170587; identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.455
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.409
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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