Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_0136Conserved hypothetical protein; Involved in positive regulation of motility and negative regulation of biofilm formation. (205 aa)    
Predicted Functional Partners:
cdgJ
Conserved hypothetical protein; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP). Positively regulates motility and negatively regulates biofilm formation.
       0.790
VC_0134
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.668
VC_0135
Lysophospholipase L2; Similar to PID:1449198; identified by sequence similarity; putative.
       0.567
VC_A0983
L-lactate permease, putative; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
      
 0.559
nhaA
Na+/H+ antiporter protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Contributes to the survival of V.cholerae during the stationary and exponential growth phases in a saline environment.
      
 0.553
alaE
Conserved hypothetical protein; Exports L-alanine; Belongs to the AlaE exporter family.
      
 0.547
VC_1069
Glyceraldehyde 3-phosphate dehydrogenase; Similar to GB:L07499 SP:P34918 PID:410113; identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
       0.487
VC_1083
Hypothetical protein; Identified by Glimmer2; putative.
    
   0.466
VC_A0189
Response regulator; Similar to PID:1736859 PID:1736868; identified by sequence similarity; putative.
    
   0.466
VC_1071
Transporter, putative; Similar to GP:3128308; identified by sequence similarity; putative.
       0.459
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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