Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_0166Transcriptional regulator, TetR family; Similar to GB:L42023 SP:P44923 PID:1005987 PID:1220997 PID:1205140; identified by sequence similarity; putative. (198 aa)    
Predicted Functional Partners:
VC_0165
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
     
 0.835
VC_0164
Multidrug resistance protein, putative; Similar to GB:L42023 PID:1005991 PID:1220999 PID:1205142 SP:Q57124; identified by sequence similarity; putative; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
     
 0.829
VC_0163
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.565
VC_A0246
SgaT protein; Similar to GB:U14003 SP:P39301 PID:537034 GB:U00096 PID:2367358; identified by sequence similarity; putative.
      
 0.559
VC_A0182
Sigma-54 dependent transcriptional regulator; Similar to SP:P37013 GB:D28595 GB:U03846 PID:434587 PID:434588; identified by sequence similarity; putative.
      
 0.541
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 
 0.533
rep
ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
  
    0.527
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
   
    0.450
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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