Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
coaDLipopolysaccharide core biosynthesis protein KdtB; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (164 aa)    
Predicted Functional Partners:
coaE
Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
  
 0.978
coaBC
DNA/pantothenate metabolism flavoprotein; Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'- phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.975
coaA
Pantothenate kinase; Similar to GB:M36321 SP:P15044 GB:M90071 PID:145560 PID:145561; identified by sequence similarity; putative.
     
 0.954
VC_A0769
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.902
VC_0146
Conserved hypothetical protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
 
  
 0.837
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
   
 0.796
VC_0223
ADP-heptose--LPS heptosyltransferase II, putative; Similar to GB:L42023 SP:P44011 PID:1003930 PID:1222457 PID:1204774; identified by sequence similarity; putative.
     
 0.757
VC_0681
Riboflavin kinase/FMN adenylyltransferase; Similar to GB:U00096 PID:1786208; identified by sequence similarity; putative; Belongs to the ribF family.
 
   
 0.713
rsmJ
Conserved hypothetical protein; Specifically methylates the guanosine in position 1516 of 16S rRNA.
  
  
 0.633
hisI
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; Similar to SP:P06989 GB:D43637 GB:U02072 GB:X03974 PID:41700; identified by sequence similarity; putative; In the C-terminal section; belongs to the PRA-PH family.
     
 0.619
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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