STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kdkAConserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. (251 aa)    
Predicted Functional Partners:
VC_0233
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
   
 0.963
VC_0225
Lipopolysaccharide biosynthesis protein, putative; Similar to GB:L42023 PID:1003419 PID:1222185 PID:1204517 PID:1573227; identified by sequence similarity; putative.
 
  
 0.935
VC_0228
Hypothetical protein; Identified by Glimmer2; putative.
    
  0.886
VC_2044
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the glutaredoxin family. Monothiol subfamily.
    
 
 0.805
VC_0237
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
  0.655
VC_0223
ADP-heptose--LPS heptosyltransferase II, putative; Similar to GB:L42023 SP:P44011 PID:1003930 PID:1222457 PID:1204774; identified by sequence similarity; putative.
 
  
 0.640
lpxL
Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
 
  
 0.627
VC_0236
ADP-heptose--LPS heptosyltransferase II; Similar to PID:1916630; identified by sequence similarity; putative.
    
 0.605
VC_0239
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
 0.583
epsH
General secretion pathway protein H; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity). Required for secretion of cholera toxin through the outer membrane.
  
     0.583
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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