Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (373 aa)    
Predicted Functional Partners:
rfbA
Mannose-1-phosphate guanylyltransferase; Similar to GB:X59554 SP:Q07024 PID:48383; identified by sequence similarity; putative.
 
  
 0.975
VC_0934
Capsular polysaccharide biosynthesis glycosyltransferase, putative; Similar to GB:U00096 SP:P71241 PID:1407618 PID:1736749 PID:1736753; identified by sequence similarity; putative.
 
  
 0.972
VC_0244
Perosamine synthase; Similar to GB:X59554 PID:48386; identified by sequence similarity; putative; Belongs to the DegT/DnrJ/EryC1 family.
  
 
 0.940
rfbB
Phosphomannomutase; Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides; Belongs to the phosphohexose mutase family.
  
  
 0.935
VC_0247
lipopolysaccharide/O-antigen transport protein; Similar to GB:X59554 PID:48389; identified by sequence similarity; putative.
  
  
 0.871
VC_0246
lipopolysaccharide/O-antigen transport protein; Similar to GB:X59554 PID:48388; identified by sequence similarity; putative.
  
  
 0.836
VC_0245
rfbG protein; Similar to GB:X59554 PID:48387; identified by sequence similarity; putative.
  
  
 0.789
VC_0260
Mannosyl-transferase; Similar to PID:1929425; identified by sequence similarity; putative.
  
  
 0.782
VC_0263
Galactosyl-transferase, putative; Similar to PID:1929427; identified by sequence similarity; putative.
  
  
 0.747
hldD
ADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
  
 
 0.723
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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