Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_0302Conserved hypothetical protein; Identified by Glimmer2; putative. (396 aa)    
Predicted Functional Partners:
VC_0303
Sensor histidine kinase; Similar to GP:2808665; identified by sequence similarity; putative.
     
 0.749
VC_0299
DNA polymerase III, epsilon subunit, putative; Similar to GB:AE000657; identified by sequence similarity; putative.
       0.748
VC_0300
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.748
acsA
acetyl-CoA synthase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
       0.654
VC_0301
Hypothetical protein; Identified by Glimmer2; putative.
       0.545
VC_1121
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.540
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
       0.497
VC_1698
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
    0.468
VC_A0102
CbbY family protein; Similar to GB:U00096 PID:1789046; identified by sequence similarity; putative.
  
  
 0.453
VC_A0662
CbbY family protein; Similar to GB:U00096 PID:1789046; identified by sequence similarity; putative.
  
  
 0.453
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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