STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0344N-acetylmuramoyl-L-alanine amidase; Similar to SP:P26365 GB:Z11831 PID:304914 PID:42068 PID:537010; identified by sequence similarity; putative. (581 aa)    
Predicted Functional Partners:
VC_2676
Cell division protein FtsN, putative; Similar to GB:L19201 SP:P29131 GB:L14281 PID:290448 PID:305036; identified by sequence similarity; putative.
 
 0.948
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).
     
 0.905
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
   
 0.899
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.887
VC_0343
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.874
lolA
Outer membrane lipoproteins carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity).
  
 
 
 0.858
VC_0099
glpG protein; Similar to GB:M54940 SP:P09391 GB:M96795 PID:146185 PID:146193; identified by sequence similarity; putative.
  
 
 0.851
VC_1981
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.851
VC_0414
Hypothetical protein; Identified by Glimmer2; putative.
    
 0.841
VC_2662
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
 
 0.832
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.