STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0405MSHA biogenesis protein MshE; Similar to PID:791156 PID:791159; identified by sequence similarity; putative. (575 aa)    
Predicted Functional Partners:
VC_0406
MSHA biogenesis protein MshG; Similar to PID:1016255 PID:1016256; identified by sequence similarity; putative.
 
 
 0.991
pilC
Type IV pilin biogenesis protein PilC; Involved in the translocation of the type IV pilin; Belongs to the GSP F family.
 
 
 0.962
epsF
General secretion pathway protein F; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity). Required for secretion of cholera toxin through the outer membrane.
 
 
 0.961
VC_0409
MSHA pilin protein MshA; Similar to GP:673504; identified by sequence similarity; putative.
 
 0.955
VC_0408
MSHA pilin protein MshB; Similar to GB:X77217 PID:496758; identified by sequence similarity; putative.
 
 0.954
VC_0399
MSHA biogenesis protein MshI; Similar to PID:791156 PID:791153; identified by sequence similarity; putative.
   
 
 0.937
VC_0411
MSHA pilin protein MshD; Similar to GB:X77217 PID:673506 PID:673507; identified by sequence similarity; putative.
 
 0.921
VC_0402
MSHA biogenesis protein MshL; Similar to PID:791156; identified by sequence similarity; putative.
 
  
 0.919
epsL
General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity). Required for secretion of cholera toxin through the outer membrane.
  
 
 0.879
tcpE
Toxin co-regulated pilus biosynthesis protein E; Probably involved in cholera toxin receptor (GM1) interaction in order to bring the cells within close proximity of the ganglioside for efficient toxin delivery.
 
 
 0.875
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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