STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_0414Hypothetical protein; Identified by Glimmer2; putative. (1252 aa)    
Predicted Functional Partners:
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
  
 0.973
VC_0412
Hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.969
VC_0157
Alkaline serine protease; Similar to GB:M25499 SP:P16588 PID:155251; identified by sequence similarity; putative; Belongs to the peptidase S8 family.
  
 0.957
VC_0409
MSHA pilin protein MshA; Similar to GP:673504; identified by sequence similarity; putative.
 
   
 0.938
VC_A0849
Hypothetical protein; Identified by Glimmer2; putative.
  
 0.935
VC_1250
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
 0.916
VC_0411
MSHA pilin protein MshD; Similar to GB:X77217 PID:673506 PID:673507; identified by sequence similarity; putative.
 
   
 0.907
VC_A0783
Arylesterase; Similar to GB:X71116 SP:Q07792 PID:296403; identified by sequence similarity; putative.
   
 0.906
VC_0239
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.880
VC_0410
MSHA pilin protein MshC; Similar to GB:X77217 PID:496759; identified by sequence similarity; putative.
 
   
 0.880
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.