Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
VC_0428Conserved hypothetical protein; Identified by Glimmer2; putative. (145 aa)    
Predicted Functional Partners:
VC_0429
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
    0.773
VC_0430
Immunogenic protein; Similar to SP:P12920 PID:144105; identified by sequence similarity; putative.
 
     0.771
VC_0426
Hypothetical protein; Identified by Glimmer2; putative.
       0.487
VC_A1017
methylated-DNA--protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.479
VC_2530
Sigma-54 modulation protein, putative; Similar to PID:2317739; identified by sequence similarity; putative.
   
  
 0.476
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
   
    0.450
VC_1433
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
  
 0.440
VC_A0159
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
  
 0.440
ompW
Outer membrane protein OmpW; Similar to SP:P17266 PID:48376 PID:2199526; identified by sequence similarity; putative.
  
  
 0.434
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
  
 0.429
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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